A human DEAD box protein with partial homology to heterogeneous nuclear ribonucleoprotein U

Gene. 1994 Jan 28;138(1-2):243-5. doi: 10.1016/0378-1119(94)90816-8.

Abstract

In a previous report, we showed that a novel DEAD box protein-encoding gene, DDX1, was amplified in two retinoblastoma (RB) cell lines. In addition to the eight conserved motifs that characterize all DEAD box proteins, the deduced amino acid sequence of DDX1 contains a subregion with considerable homology to heterogeneous nuclear ribonucleoprotein U.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cell Line
  • Conserved Sequence
  • DEAD-box RNA Helicases
  • Eye Neoplasms
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Hominidae / genetics*
  • Humans
  • Molecular Sequence Data
  • Peptide Hydrolases / genetics*
  • RNA Helicases
  • RNA Nucleotidyltransferases / genetics*
  • Retinoblastoma
  • Ribonucleoproteins / genetics*
  • Sequence Homology, Amino Acid
  • Tumor Cells, Cultured

Substances

  • Heterogeneous-Nuclear Ribonucleoproteins
  • Ribonucleoproteins
  • RNA Nucleotidyltransferases
  • Peptide Hydrolases
  • DDX1 protein, human
  • DEAD-box RNA Helicases
  • RNA Helicases

Associated data

  • GENBANK/X70649