The I kappa B proteins: members of a multifunctional family

Trends Genet. 1993 Dec;9(12):427-33. doi: 10.1016/0168-9525(93)90106-r.

Abstract

The I kappa B proteins bind to Rel/NF-kappa B transcription factors and modulate their activities. Although originally described only as cytoplasmic inhibitors of Rel/NF-kappa B transcription complexes, it is now clear that I kappa B proteins also have other functions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • DNA-Binding Proteins / physiology*
  • I-kappa B Proteins
  • Molecular Sequence Data
  • Proto-Oncogene Proteins / physiology*
  • Transcription Factors / physiology*

Substances

  • DNA-Binding Proteins
  • I-kappa B Proteins
  • Proto-Oncogene Proteins
  • Transcription Factors