A model of the Drosophila melanogaster glycerol-3-phosphate oxidase-encoding gene

J L Ross; M B Davis; R J MacIntyre; S W McKechnie

doi:10.1016/0378-1119(94)90759-5

A model of the Drosophila melanogaster glycerol-3-phosphate oxidase-encoding gene

Gene. 1994 Feb 25;139(2):219-21. doi: 10.1016/0378-1119(94)90759-5.

Authors

J L Ross¹, M B Davis, R J MacIntyre, S W McKechnie

Affiliation

¹ Department of Genetics and Developmental Biology, Monash University, Clayton, Australia.

PMID: 8112608
DOI: 10.1016/0378-1119(94)90759-5

Abstract

We have sequenced the Drosophila melanogaster gene encoding the mitochondrial (mt) enzyme glycerol-3-phosphate oxidase (GPO; EC 1.1.99.5) that is involved in flight and alcohol metabolism. Available data suggests a simple model for this gene that includes four exons. Exon I contains a mt import signal, exon II, a transmembrane segment and an FAD-binding site, and exon IV, an iron-sulfur centre.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alternative Splicing / genetics
Animals
Base Sequence
Carbohydrate Dehydrogenases / genetics*
Drosophila melanogaster / enzymology
Drosophila melanogaster / genetics*
Exons / genetics*
Genes, Insect / genetics*
Introns / genetics*
Mitochondria, Muscle / enzymology
Molecular Sequence Data
Promoter Regions, Genetic / genetics

Substances

Carbohydrate Dehydrogenases
3-glycerophosphate dehydrogenase