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Trends Genet. 1993 Apr;9(4):106-12.

Hox genes and pattern formation in the branchial region of the vertebrate head.

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MRC National Institute for Medical Research, Mill Hill, London, UK.


The conservation of molecular mechanisms in evolution has stimulated interest in comparative embryology, and the Hox/HOM-C homeobox complexes are among the best examples of the remarkable conservation between species. An important region associated with Hox patterning is the head, where the evolutionary and molecular studies have reawakened interest in the cellular processes and complex interactions required to regulate craniofacial morphogenesis.

[Indexed for MEDLINE]

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