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Psychiatry Res. 1993 Mar;46(3):261-7.

Possible association of c-Harvey-Ras-1 (HRAS-1) marker with autism.

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  • 1National Institute for Health and Medical Research, Tours, France.


We tested for an association between autism and genes coding for enzymes involved in monoaminergic metabolism and for a linked marker, c-Harvey-Ras-1 (HRAS 1), using restriction fragment length polymorphisms. We did not find evidence of an association between autism and genes coding for tyrosine hydroxylase, dopamine-beta-hydroxylase (DBH), and tryptophan hydroxylase. However, we report a positive association between autism and the locus containing the gene for HRAS-1.

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