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Experientia. 1993 Feb 15;49(2):179-81.

Marine antitumor agents: 14-deoxycrassin and pseudoplexaurol, new cembranoid diterpenes from the Caribbean gorgonian Pseudoplexaura porosa.

Author information

1
Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346.

Abstract

Two new cytotoxic antitumor diterpenoids of the cembrane class, named 14-deoxycrassin (3) and pseudoplexaurol (4), have been isolated from the Caribbean gorgonian octocoral Pseudoplexaura porosa. The structure of lactone 3, possessing the infrequently encountered alpha-methylene-delta-lactone ring, has been established from spectral and chemical data and that of alcohol 4 has been established from spectral data.

PMID:
8095027
DOI:
10.1007/bf01989427
[Indexed for MEDLINE]

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