Format

Send to

Choose Destination
Am J Public Health. 1994 Sep;84(9):1421-8.

Prenatal alcohol exposure, birthweight, and measures of child size from birth to age 14 years.

Author information

1
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195.

Abstract

OBJECTIVES:

The purpose of the study was to examine the effect of prenatal alcohol exposure on offspring's weight, height, and head circumference from birth through 14 years of age.

METHODS:

This longitudinal prospective study examined a cohort of approximately 500 offspring (oversampled for heavier drinkers and stratified for smoking from a population of 1529 women in prenatal care at the 5th gestational month) at birth; 8 and 18 months; and 4, 7, and 14 years of age. Covariates were examined by means of multiple regression. Birth size measures were also examined as predictors of 7-year neurodevelopmental outcomes.

RESULTS:

Effects of alcohol were observed on weight, length, and head circumference at birth; these effects were not altered by adjustment for covariates including smoking. However, the birthweight effect is clearly transient: although alcohol effects remained observable at 8 months, they were not measurable thereafter through age 14 years.

CONCLUSIONS:

In this population-based sample, neither birthweight nor any later size measure was as useful an indicator of the enduring effects of prenatal alcohol exposure as were certain neurodevelopmental outcomes.

PMID:
8092365
PMCID:
PMC1615145
DOI:
10.2105/ajph.84.9.1421
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center