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Nutr Rev. 1994 Jul;52(7):242-5.

The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland.

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USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.


The U.S. National Cancer Institute and the Finnish National Public Institute jointly sponsored a large double-blind, placebo-controlled primary-prevention trial to examine the effects of vitamin E and beta-carotene supplementation on reducing the incidence of lung cancers in male smokers, ages 50-69 years. Supplementation did not result in a significant reduction in lung cancer, and a higher incidence of lung cancer was observed in the group receiving beta-carotene. These results should be examined within the context of the population studied before they are cited as definitive.

[Indexed for MEDLINE]

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