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Genomics. 1994 May 1;21(1):150-9.

Cloning of two novel ABC transporters mapping on human chromosome 9.

Author information

1
Centre d'Immunologie, INSERM-CNRS de Marseille-Luminy, France.

Abstract

The family of ATP binding cassette (ABC) transporters or traffic ATPases is composed of several membrane-associated proteins that transport a great variety of solutes across cellular membranes. Two novel mammalian members of the family, ABC1 and ABC2, have been identified by a PCR-based approach. They belong to a group of traffic ATPases encoded as a single multifunctional protein, such as CFTR, STE 6, and P-glycoproteins. Their peculiar structural features and close relationship to ABC transporters involved in nodulation suggest that ABC1 and ABC2 define a novel subgroup of mammalian traffic ATPases.

PMID:
8088782
DOI:
10.1006/geno.1994.1237
[Indexed for MEDLINE]
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