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J Bacteriol. 1994 Sep;176(18):5847-51.

Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli.

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1
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138.

Abstract

We report here the identification and characterization of pgm, a gene in Escherichia coli that encodes the enzyme phosphoglucomutase, specifically required for the catalysis of the interconversion of glucose 1-phosphate and glucose 6-phosphate. The predicted amino acid sequence of the pgm gene is highly conserved in E. coli, Acetobacter xylinum, Saccharomyces cerevisiae, rabbits, and humans. pgm deletion mutant strains are deficient in phosphoglucomutase activity.

PMID:
8083177
PMCID:
PMC196791
[Indexed for MEDLINE]
Free PMC Article
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