Format

Send to

Choose Destination
See comment in PubMed Commons below
J Chromatogr A. 1994 Jul 15;674(1-2):73-86.

Confirmatory tests for drugs in the workplace by gas chromatography-mass spectrometry.

Author information

1
Chemistry and Drug Metabolism Section, National Institute on Drug Abuse, Baltimore, MD 21224.

Abstract

The Mandatory Guidelines for Federal Workplace Drug Testing Programs require the use of gas chromatography-mass spectrometry (GC-MS) for the confirmation of presumptive positive urine specimens. This review focuses upon GC-MS methods developed specifically for forensic confirmation of amphetamine, methamphetamine, 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (THC-acid), benzoylecgonine, morphine, codeine and phencyclidine in urine for purposes of workplace drug testing. In addition, current laboratory issues pertaining to each drug class are reviewed. Generally, drug assays utilized either liquid-liquid or solid-phase extraction methods, derivatization if necessary, and GC-MS detection operating in the selected ion monitoring mode or by full scan acquisition.

PMID:
8075776
DOI:
10.1016/0021-9673(94)85218-9
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center