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Zhonghua Nei Ke Za Zhi. 1994 Feb;33(2):83-6.

[Effects of Epimedium sagittatum on immunopathology and extracellular matrices in rats with chronic renal insufficiency].

[Article in Chinese]

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  • 1Department of Nephrology, General Hospital of Chinese PLA, Beijing.


Chinese herb medicine, Epimedium sagittatum (EP), was used to treat animal models of chronic renal insufficiency induced in Wistar rats with 7/8 nephrectomy. The results showed: 1. EP decreased significantly the level of BUN and serum creatinine in the rats. 2. EP inhibited the hypertrophy of glomeruli in the rats. 3. EP inhibited deposition of IgG, C3, Fib and FN along the glomerular capillary walls in these rats.

[PubMed - indexed for MEDLINE]
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