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Convuls Ther. 1994 Jun;10(2):171-6.

Stimulus dose-titration in ECT: a 2-year clinical experience.

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  • 1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.


One hundred and thirty-four patients referred for electroconvulsive therapy (ECT) over a 2-year period underwent standardized stimulus dose-titration. No significant adverse events were associated with the dose-titration procedure. Our data demonstrate that seizure threshold increases with age (p = 0.0001) and is higher with bilateral electrode placement (p = 0.0001). Contrary to other studies, our data show the effect of gender is not statistically significant (p = 0.54). If consensus regarding optimal dosing strategies relative to seizure threshold can be achieved, dose-titration may be adopted as a clinically useful step in optimizing ECT technique.

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