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Ugeskr Laeger. 1994 Jun 6;156(23):3495-8.

[Fish oils and rheumatoid arthritis. A randomized and double-blind study].

[Article in Danish]

Author information

1
Reumatologisk afdeling, Amtssygehuset i Herlev.

Abstract

The effect of dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) on disease variables in patients with active rheumatoid arthritis was evaluated in a multicentre, randomized and double blind study. Fifty-one patients with active rheumatoid arthritis were included from three Danish hospital Departments of Rheumatology. The patients were allocated to 12 weeks of treatment with either six n-3 PUFA capsules (3.6 g) or six capsules with a fat composition averaging the Danish diet. Small but significant improvements in morning stiffness, joint tenderness and C-reactive protein were observed. There were no serious side-effects. Dietary supplementation with n-3 PUFA in patients with active rheumatoid arthritis has a modest effect on three out of eight disease variables, without effect on other traditional parameters for monitoring disease activity.

PMID:
8066866
[Indexed for MEDLINE]

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