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J Reprod Med. 1994 May;39(5):412-4.

Primary syphilis and nonimmune fetal hydrops in a penicillin-allergic woman. A case report.

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Department of Obstetrics and Gynecology, University of Wisconsin Medical School, Milwaukee 53201.


The incidence of congenital syphilis is on the rise. Penicillin continues to be the drug of choice for it during pregnancy. A penicillin-allergic woman with primary stage syphilis who was treated initially with erythromycin presented with fever and nonimmune fetal hydrops secondary to an intrauterine syphilitic infection. Following desensitization and penicillin therapy the fetal hydrops disappeared, the pregnancy continued to term, and the patient delivered a small-for-gestational-age but other-wise normal infant who continued to do well up to 1 year of age.

[Indexed for MEDLINE]

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