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Gene. 1994 Aug 5;145(2):313-4.

Cloning and sequence analysis of the human SNAP25 cDNA.

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  • 1Human Genome Center, University of Tokyo, Japan.


During the screening of human brain-specific cDNAs by a modified differential hybridization analysis, we found a clone which was highly and specifically expressed in the (adult) brain. This clone was subjected to nucleotide sequence analysis and proven to be a nearly full-length cDNA of a human homologue of the previously reported mouse synaptosomal-associated protein 25 (mSNAP25). The human SNAP25 (hSNAP25) and mSNAP25 showed perfect amino-acid sequence conservation.

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