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Br J Dermatol. 1994 Jul;131(1):124-9.

Photoallergic contact dermatitis to oxybenzone.

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Department of Dermatology, Ninewells Hospital and Medical School, Dundee, U.K.


A 21-year-old woman developed an erythematous papulovesicular eruption of photo-exposed sites, following the use of an oxybenzone-containing sunscreen. Patch testing, photopatch testing, phototesting, and histology produced findings strongly suggestive of oxybenzone photoallergy. Photopatch testing with a monochromator source showed abnormal UVA responses, with evidence of immediate urticaria, and delayed-onset dermatitis. Sun-barrier use is associated with a risk of the development of contact or photocontact allergic reactions. The benzophenones are frequently used in high-protection factor sun-barrier preparations, and appear to have a particular ability to induce such responses.

[Indexed for MEDLINE]

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