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Am J Hematol. 1994 Aug;46(4):358-62.

Molecular analysis of an asymptomatic Ph-positive CML patient with 27 years of prolonged remission.

Author information

1
Department of Molecular Genetics, Rambam Medical Center, Haifa, Israel.

Abstract

We describe the results of clinical, cytogenetic, and molecular biological studies of a patient who, after two courses of treatment with Busulphan, has remained free of symptoms of Philadelphia chromosome-positive chronic myeloid leukemia for 27 years, except for the persistence of a Ph1 chromosome and the presence of its transcribed chimeric mRNA.

PMID:
8037191
[Indexed for MEDLINE]

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