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Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (Hawthorn) flower heads.

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1
Pharmacologie de la RĂ©gulation, CNRS Institut de Physiologie-2, Toulouse, France.

Abstract

A hydro-alcoholic extract from Crataegus o. (Co) flower heads inhibited thromboxane A2 (TXA2) biosynthesis in vitro. This present study aims to find out which are the active principles. The main components, as revealed by chromatography, were tested. We also took into consideration catechin and epicatechin: although they do not appear as such with chromatography because of their polymerisation or-and condensed structure, these two proanthocyanidins seem to play a major role in the mentioned activity of the plant.

PMID:
8022851
[Indexed for MEDLINE]
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