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Microbios. 1994;78(314):7-16.

Anti-bacillus substance in the marine sponge, Hyatella species, produced by an associated Vibrio species bacterium.

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Department of Applied Biochemistry, Hiroshima University, Japan.


The bacterial isolate, M22-1, belonging to the genus Vibrio was obtained from an homogenate of the sponge, Hyatella sp. The bacterium was cultured in marine agar and was found to produce an anti-Bacillus compound. The substance was chemically identified as a peptide antibiotic, an andrimid. The same substance was found in the sponge extract, suggesting that the active component was synthesized by the associated microorganism.

[Indexed for MEDLINE]

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