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Genomics. 1994 Mar 1;20(1):114-5.

Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22.

Author information

1
Cell Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

Abstract

In this study, we map the chromosomal position of the gene that encodes the type II receptor of TGF-beta (HGM symbol TGFBR2), a multifunctional regulator of cell proliferation and differentiation. Using a full-length cDNA and a genomic probe in Southern blot analysis of a human x rodent somatic cell hybrid panel and by direct fluorescence in situ hybridization to normal metaphase chromosomes, we show that the TGFBR2 gene maps to 3p22.

PMID:
8020936
DOI:
10.1006/geno.1994.1134
[Indexed for MEDLINE]

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