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Biochim Biophys Acta. 1994 Jun 21;1218(2):229-31.

Cloning and sequencing of the cDNA encoding human glutaredoxin.

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Department of Biochemistry, Kyushu University School of Medicine, Fukuoka, Japan.


Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.

[Indexed for MEDLINE]

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