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Trends Microbiol. 1994 Apr;2(4):131-6.

Group A streptococcal immunoglobulin-binding proteins: adhesins, molecular mimicry or sensory proteins?

Author information

1
Dept of Microbiology, University of Minnesota, Minneapolis 55455.

Abstract

Pathogenic streptococci express multiple immunoglobulin-binding proteins (IGPs) on their surface that are similar in sequence and structure to the antiphagocytic M proteins. Both are evolutionary products of a duplicated ancestral gene and are components of the Vir gene cluster. Except for M proteins, there is little direct experimental evidence to implicate IGPs in pathogenesis. Several functions of IGPs are postulated and discussed.

PMID:
8012756
[Indexed for MEDLINE]

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