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Biophys Chem. 1994 May;50(1-2):73-85.

Connectin, an elastic protein of striated muscle.

Author information

1
Department of Biology, Faculty of Science, Chiba University, Japan.

Abstract

Connectin, also called titin, a giant elastic protein of striated muscle (approximately 3000 kDa) mainly consists of fibronectin type III and immunoglobulin C2 globular domains, the beta-sheets of which are parallel to the main axis of the molecule. One connectin molecule runs through the I band and binds onto the myosin filament up to the M line starting from the Z line. It positions the myosin filament at the center of a sarcomere. Connectin is also responsible for resting tension generation. Biodiversity of the connectin family exists in invertebrate muscle.

PMID:
8011942
DOI:
10.1016/0301-4622(94)85021-6
[Indexed for MEDLINE]

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