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Zhongguo Zhong Yao Za Zhi. 1994 Feb;19(2):105-7, 128.

[Analgesic effect and no physical dependence of amygdalin].

[Article in Chinese]

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School of Pharmacy, Second Military Medical University, Shanghai.


Analgesic effect of amygdalin (AM) in mice was observed in hot plate and acetic acid-induced writhing tests. AM did not induce tolerance as morphine did, and did not cause morphine-characteristic tail-erecting response in mice. Mice given AM and then challenged with nalorphine showed no jumping response. AM could not substitute for morphine in morphine-addicted rats in relieving withdrawal syndrome. No antiinflammatory activity was found with AM.

[Indexed for MEDLINE]

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