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Protein Sci. 1994 Apr;3(4):650-68.

Protein folding dynamics: the diffusion-collision model and experimental data.

Author information

1
Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138.

Abstract

The diffusion-collision model of protein folding is assessed. A description is given of the qualitative aspects and quantitative results of the diffusion-collision model and their relation to available experimental data. We consider alternative mechanisms for folding and point out their relationship to the diffusion-collision model. We show that the diffusion-collision model is supported by a growing body of experimental and theoretical evidence, and we outline future directions for developing the model and its applications.

PMID:
8003983
PMCID:
PMC2142854
DOI:
10.1002/pro.5560030413
[Indexed for MEDLINE]
Free PMC Article

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