A report of four AIDS-related psychiatric cases in Honduras is presented. (2,544 AIDS cases have been reported up to April '93. In the sole city of San Pedro Sula, 1,000 cases have been reported). Measures are suggested for an improved psychiatrical and psychological care of patients (either seropositive patients or AIDS healthy carriers): the former would be helped toward a smoother acceptance of an impending death, the latter could be in a better position to fight against social prejudice and discrimination.