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Br J Rheumatol. 1994 Nov;33(11):1007-11.

Genetics of osteoporosis.

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1
Garvan Institute of Medical Research, Department of Endocrinology, St Vincent's Hospital, Sydney, Australia.

Abstract

Identification of the major contribution of genetic factors in determination of peak bone mass at skeletal maturity and possibly on subsequent age-related bone loss has led to efforts to identify possible mechanisms. Recent evidence suggests one mechanism relates to genetic effects on bone turnover mediated via the vitamin D system. This field of research has potential for reducing osteoporotic fracture risk by allowing interventions at different stages in life to reduce this increasing problem of ageing societies.

PMID:
7981986
[Indexed for MEDLINE]
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