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Trends Microbiol. 1994 Aug;2(8):271-7.

Microbial sialidases: does bigger always mean better?

Author information

1
Dept of Veterinary Pathobiology, University of Illinois, Urbana 61801.

Abstract

Sialidases are a superfamily of N-acylneuraminate-releasing (sialic-acid-releasing) exoglycosidases found mainly in higher eukaryotes and in some, mostly pathogenic, viruses, bacteria and protozoans. The functions of sialidases are poorly understood and, until recently, their biochemical and evolutionary relationships were unclear. A comparative approach has demonstrated the remarkable similarities and differences between nonviral sialidases, and is providing clues about their functions.

PMID:
7981969
DOI:
10.1016/0966-842x(94)90003-5
[Indexed for MEDLINE]

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