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Gene. 1994 Dec 2;150(1):207-8.

Histone-encoding genes from Pyrococcus: evidence for members of the HMf family of archaeal histones in a non-methanogenic Archaeon.

Author information

1
Department of Microbiology, Ohio State University, Columbus 43210.

Abstract

Two genes, designated hpyA1 and hpyA2, have been cloned and sequenced from Pyrococcus strain GB-3a. They are predicted to encode proteins (HPyA1 and HPyA2, respectively) that are approx. 60% identical to the histones HMf and HMt, characterized from methanogenic Archaea. These archaeal histones also contain the amino-acid sequences, conserved in eukaryotic H4 histones, that are thought to interact directly with DNA.

PMID:
7959058
DOI:
10.1016/0378-1119(94)90890-7
[Indexed for MEDLINE]

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