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Curr Opin Lipidol. 1994 Jun;5(3):166-74.

Fatty acids, hyperinsulinemia, and insulin resistance: which comes first?

Author information

1
Department of Heart and Lung Diseases, University of Göteborg, Sweden.

Abstract

The inhibiting effect of insulin on the mobilization of free fatty acids (FFA) from adipose tissue is halted in prevalent conditions with systemic insulin resistance. The nature and cause of this perturbation are unknown, but steroid hormones may be involved. The consequence is the creation or amplification of insulin resistance in muscle and liver.

PMID:
7952910
[Indexed for MEDLINE]

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