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Curr Opin Genet Dev. 1994 Aug;4(4):581-6.

Programmed cell death in Caenorhabditis elegans.

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Cold Spring Harbor Laboratory, New York.


Programmed cell death in the nematode Caenorhabditis elegans requires the activities of the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of these C. elegans genes has shown that two of them encode proteins with similarity to vertebrate cell death genes and has revealed that nematodes and mammals share a common pathway for programmed cell death.

[Indexed for MEDLINE]

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