Format

Send to

Choose Destination
J Infect Dis. 1994 Oct;170(4):873-7.

Outcomes of Bordetella pertussis infection in different age groups of an immunized population.

Author information

1
National Public Health Institute, Department in Turku, Finland.

Abstract

Outcomes of Bordetella pertussis infection were studied in 3 age groups (1-3, 4-6, and 7-15 years) during outbreaks in one day care center (n = 29) and in two elementary schools (n = 210). A total of 76 children were confirmed as having B. pertussis infection; 74 were confirmed by polymerase chain reaction (PCR) and 18 by culture. A positive PCR result was less common in children 1-3 years old than in those 4-6 (P = .006). Asymptomatic B. pertussis infection was more common in preschool children than in schoolchildren (P < .001), whereas schoolchildren presented with symptoms compatible with clinical pertussis more often than preschool children (60/210 vs. 3/29, P = .029). In the community of 12,691, the attack rate (laboratory-confirmed patients/100,000) was 317 in children < 4 years, 1838 in children 4-6 years, 2535 in children 7-15 years, and 248 in persons > 15 years. The protection provided by conventional pertussis vaccine is evidently rather short-lived, and booster vaccinations are needed to eradicate pertussis among schoolchildren and adults.

PMID:
7930729
DOI:
10.1093/infdis/170.4.873
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center