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J Antimicrob Chemother. 1994 May;33 Suppl A:31-41.

Bacterial biofilms: influence on the pathogenesis, diagnosis and treatment of urinary tract infections.

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Department of Urology, Queen's University, Kingston, Ontario, Canada.


The bacterial biofilm theory which describes bacterial populations in natural and pathogenic ecological systems in terms of a free-floating or 'planktonic' population of bacteria interacting with a more important matrix enclosed 'sessile' population of bacteria associated with or adherent to a surface, may help explain some of the problems linked to our understanding the nature of urinary tract infections. This paper reviews the role of bacterial biofilm formation in catheter-associated infection, prostatitis and struvite (infected stone) calculogenesis stressing, the importance of bacterial biofilms in the pathogenesis, persistence and hence the treatment of urinary tract infection.

[Indexed for MEDLINE]

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