Efficacy and safety of indomethacin 0.1% versus flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty. The Belgian Study Group on Glaucoma

Doc Ophthalmol. 1994;85(3):287-93. doi: 10.1007/BF01664937.

Abstract

After Argon Laser Trabeculoplasty (ALT), non steroidal anti-inflammatory drugs (Indomethacin 1% suspension and Flurbiprofen 0.03% solution) were shown to be efficient in the management of post laser inflammation. To evaluate the efficacy and safety of Indomethacin 0.1% solution versus Flurbiprofen 0.03% eyedrops in that purpose. 64 patients suffering from glaucoma were recruited in a multicenter randomized double masked study. The results demonstrate that Indomethacin 0.1% eyedrops is as efficient as Flurbiprofen 0.03% in terms of control of post ALT inflammation, with a good tolerance.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Double-Blind Method
  • Drug Tolerance
  • Endophthalmitis / drug therapy*
  • Endophthalmitis / etiology
  • Female
  • Flurbiprofen / administration & dosage
  • Flurbiprofen / adverse effects
  • Flurbiprofen / therapeutic use*
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Indomethacin / administration & dosage
  • Indomethacin / adverse effects
  • Indomethacin / therapeutic use*
  • Intraocular Pressure
  • Laser Therapy / adverse effects*
  • Male
  • Middle Aged
  • Ophthalmic Solutions
  • Trabeculectomy / adverse effects*

Substances

  • Ophthalmic Solutions
  • Flurbiprofen
  • Indomethacin