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Br J Psychiatry. 1994 May;164(5):593-9.

The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?

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Department of Psychological Medicine, University of Wales College of Medicine, Cardiff.


The evidence for a genetic contribution to schizophrenia is compelling. However, the pattern of inheritance is complex and it is usually assumed that environmental factors also have a role that will eventually be identified. We argue that this is not necessarily the case. While a hypothesis combining genetic diathesis with environmental stress cannot be disproved, it is also possible that 'non-genetic' factors consist entirely of stochastic events affecting gene expression or structure.

[Indexed for MEDLINE]

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