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Semin Cell Biol. 1994 Jun;5(3):139-47.

Forces exerted by locomoting cells.

Author information

1
Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599-7090.

Abstract

The movement of cells along substrata is a complex phenomenon involving cell extension and retraction, and cell-substratum adhesion. Knowledge is beginning to accumulate about the forces required for cell protrusion and retraction. Both of these processes also require traction to be exerted on the substratum, and new assays for these forces are under development. This review briefly discusses the forces that locomotory cells exert, in terms of both recent force measurements and possible mechanisms for their generation.

PMID:
7919227
DOI:
10.1006/scel.1994.1018
[Indexed for MEDLINE]

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