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Curr Opin Cell Biol. 1994 Jun;6(3):396-402.

The SNF/SWI family of global transcriptional activators.

Author information

1
Department of Genetics and Development, Columbia University, New York, NY 10032.

Abstract

The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by altering chromatin structure to relieve repression. Recent work shows that the SNF/SWI proteins function together in a multiprotein complex and that SNF2 has DNA-dependent ATPase activity. SNF/SWI homologs have now been identified in Drosophila, mice and humans, suggesting a conserved role in transcriptional activation.

PMID:
7917331
DOI:
10.1016/0955-0674(94)90032-9
[Indexed for MEDLINE]

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