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Biochim Biophys Acta. 1994 Sep 13;1219(1):219-22.

The nucleotide sequence of the murine Hox-D3 (Hox-4.1) gene reveals extensive identity with the human protein.

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Skin Biology Research Center of Johnson & Johnson, R.W. Johnson Pharmaceutical Research Institute, Raritan, NJ 08869.


We report the sequence of the murine Hox-D3 gene, formerly referred to as Hox-4, Hox-4.1 and Hox-4A. This gene is located on murine chromosome 2 in the Hox-D complex. The predicted Hox-D3 protein comprises 417 amino acids and displays 95% identity to the human protein. We have demonstrated that Hox-D3 is expressed in the skin, kidney and thymus, but not in lung, liver, spleen or stomach.

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