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J Med Virol. 1994 Mar;42(3):224-7.

Molecular epidemiological studies of human herpesvirus 6 in families.

Author information

1
Department of Virology, Osaka University, Japan.

Abstract

The mode of transmission of human herpesvirus 6 (HHV-6) was investigated by molecular epidemiological techniques in four families. HHV-6 was isolated from the peripheral blood of seven infants with exanthem subitum, including siblings, and from the saliva of two mothers. These isolates were examined for genetic relatedness by means of restriction enzymes analysis of purified DNA. While the profiles of the digestion patterns differed among families, they were very similar in a particular family. These results may suggest that HHV-6 is transmitted primarily from mother to child.

PMID:
7911825
DOI:
10.1002/jmv.1890420303
[Indexed for MEDLINE]

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