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J Neurosci Res. 1994 Jan;37(1):103-7.

Postnatal decrease of acetate concentration in rat cerebellum.

Author information

1
Institut de Biochimie Cellulaire du CNRS, Université de Bordeaux II, France.

Abstract

We examined the evolution of 1H-NMR detectable metabolites in rat cerebellum from the postnatal day 1-25, a period associated with intense metabolic changes as well as physiological and morphological modifications. The unexpected result reported here is the existence of a high concentration of acetate in neonatal rat cerebellum, progressively decreasing with age and maturation. In contrast, the cerebellum content of various metabolites such as N-acetyl-L-aspartate (NAA), glutamate, and aspartate increases from the first day onward.

PMID:
7908341
DOI:
10.1002/jnr.490370114
[Indexed for MEDLINE]

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