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Biochem Biophys Res Commun. 1994 Feb 28;199(1):52-5.

Isolation and mapping of a cosmid clone containing the human NAT2 gene.

Author information

1
Center for Human Genetics and Genetic Counselling, University of Bremen, Germany.

Abstract

The NAT2 gene encodes for a polymorphic arylalkylamine N-acetyltransferase and thus accounts for the human N-acetylation polymorphism. By a NAT2-specific primer set we have screened a human chromosome 8-specific cosmid library. A positive cosmid clone was mapped by fluorescence in situ hybridization to 8p22. The polymerase chain reaction followed by restriction analysis of the PCR product was used to identify allele 2 to be contained in the cosmid clone.

PMID:
7907215
DOI:
10.1006/bbrc.1994.1192
[Indexed for MEDLINE]

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