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Lancet. 1994 Jan 15;343(8890):146-7.

Single-breath nitric oxide measurements in asthmatic patients and smokers.

Author information

1
Department of Physiology, Karolinska Institute, Stockholm, Sweden.

Abstract

Exhaled nitric oxide (NO) concentrations were measured in asthmatic outpatients and in non-smoking and smoking healthy controls. In single exhalations, NO showed a peak suggestive of airway origin in both controls and asthmatic patients. The peak NO concentration was higher in asthmatic patients and lower in smokers than in non-smoking controls (p < 0.05). The findings support a role for NO in the host defence response in asthma and suggest that NO measurements can discriminate between different types of lung disorders.

PMID:
7904005
DOI:
10.1016/s0140-6736(94)90935-0
[Indexed for MEDLINE]

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