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J Affect Disord. 1994 Dec;32(4):225-31.

A 24-month follow-up study of unipolar subjects: a comparison between lithium and fluvoxamine.

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  • 1Dipartimento di Scienze Neuropsichiche, Universit√† degli Studi di Milano, Italy.


The authors compared rates of new episodes in a sample of 64 unipolar subjects treated with fluvoxamine (n = 32) and lithium (n = 32) during a follow-up period of 24 months. Unipolar patients on lithium treatment had a worse outcome with a higher frequency of new recurrences compared with of new recurrences compared with patients on fluvoxamine during the course of preventive treatment.

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