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J Consult Clin Psychol. 1995 Feb;63(1):90-100.

Symptoms versus a diagnosis of depression: differences in psychosocial functioning.

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Department of Psychology, Northwestern University, Evanston, Illinois 60208-2710.


In studies of clinical depression, individuals who demonstrate elevated levels of symptoms but do not meet interview-based diagnostic criteria are typically labeled as false positive and eliminated from further consideration. However, the implicit assumption that false-positive participants differ in important ways from true-positive (i.e., diagnosed) participants has not been tested systematically. This study compared the functioning of true-positive, false-positive, and true-negative adolescents on clinical and psychosocial functioning. Although the false-positive participants manifested higher levels of current and future psychopathology than did the true-negative participants, they did not differ significantly from the true-positive participants on most of the measures of psychosocial dysfunction. "False positive," therefore, is not a benign condition.

[Indexed for MEDLINE]

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