Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer

Hum Gene Ther. 1994 Nov;5(11):1385-99. doi: 10.1089/hum.1994.5.11-1385.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Antibody Formation
  • Carcinoma / secondary*
  • Carcinoma / therapy*
  • Clinical Protocols
  • Colorectal Neoplasms*
  • DNA, Recombinant / administration & dosage*
  • Female
  • Gene Transfer Techniques*
  • HLA-B7 Antigen / biosynthesis
  • HLA-B7 Antigen / genetics
  • HLA-B7 Antigen / immunology
  • HLA-B7 Antigen / therapeutic use*
  • Humans
  • Immunity, Cellular
  • Immunotherapy / adverse effects
  • Immunotherapy / methods*
  • Informed Consent
  • Injections, Intralesional
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / therapy*
  • Male
  • Recombinant Fusion Proteins / biosynthesis
  • Recombinant Fusion Proteins / immunology

Substances

  • DNA, Recombinant
  • HLA-B7 Antigen
  • Recombinant Fusion Proteins