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Ophthalmology. 1995 Mar;102(3):388-92.

Replacing ganciclovir implants.

Author information

1
Center for Eye Research, Harvard Medical School, Boston.

Abstract

PURPOSE:

The authors report their surgical experience replacing empty ganciclovir implants in patients with acquired immune deficiency syndrome (AIDS)-related cytomegalovirus (CMV) retinitis.

METHODS:

A chart review of all patients receiving two or more ganciclovir implants was performed.

RESULTS:

Nine eyes in eight patients received two or more implants. The average time before a second implant was needed was 6 months. Cytomegalovirus retinitis was controlled in all patients except one. Three patients required intermittent intravenous exogenous anti-CMV therapy, one for persistent CMV retinitis and two for systemic CMV. Visual acuity of 20/40 or better was maintained in five of eight patients, despite a longstanding history of CMV retinitis.

CONCLUSION:

In this small series, most patients retained good vision after ganciclovir implant replacement.

PMID:
7891975
DOI:
10.1016/s0161-6420(95)31010-x
[Indexed for MEDLINE]

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