[Direct approach for demonstrating free radical phenomena during equine postanesthetic myopathy: preliminary study]

D Serteyn; J Pincemail; E Mottart; I Caudron; C Deby; G Deby-Dupont; C Philippart; M Lamy

[Direct approach for demonstrating free radical phenomena during equine postanesthetic myopathy: preliminary study]

Can J Vet Res. 1994 Oct;58(4):309-12.

[Article in French]

Authors

D Serteyn¹, J Pincemail, E Mottart, I Caudron, C Deby, G Deby-Dupont, C Philippart, M Lamy

Affiliation

¹ Service de chirurgie des grands animaux et d'anesthésiologie, Faculté de médecine vétérinaire, Université de Liège, Belgique.

PMID: 7889465
PMCID: PMC1263720

Abstract

This preliminary study demonstrated the existence of a free radical generation during an experimental postischemic muscular reperfusion in a halothane anesthetized horse. The authors used alpha-phényl-N-tert-butylnitrone as a spin trap agent and the electronic paramagnetic resonance method to observe in vivo a free radical generation.

Publication types

English Abstract

MeSH terms

Anesthesia, Inhalation / adverse effects
Anesthesia, Inhalation / veterinary*
Animals
Cyclic N-Oxides
Female
Free Radicals / metabolism*
Halothane / adverse effects
Horse Diseases / etiology
Horse Diseases / metabolism*
Horses
Muscular Diseases / metabolism
Muscular Diseases / veterinary*
Nitrogen Oxides
Reperfusion Injury / metabolism
Reperfusion Injury / veterinary*
Spin Labels

Substances

Cyclic N-Oxides
Free Radicals
Nitrogen Oxides
Spin Labels
phenyl-N-tert-butylnitrone
Halothane