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Arch Ophthalmol. 1995 Mar;113(3):325-32.

Optical coherence tomography of the human retina.

Author information

1
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge.

Abstract

OBJECTIVE:

To demonstrate optical coherence tomography for high-resolution, noninvasive imaging of the human retina. Optical coherence tomography is a new imaging technique analogous to ultrasound B scan that can provide cross-sectional images of the retina with micrometer-scale resolution.

DESIGN:

Survey optical coherence tomographic examination of the retina, including the macula and optic nerve head in normal human subjects.

SETTING:

Research laboratory.

PARTICIPANTS:

Convenience sample of normal human subjects.

MAIN OUTCOME MEASURES:

Correlation of optical coherence retinal tomographs with known normal retinal anatomy.

RESULTS:

Optical coherence tomographs can discriminate the cross-sectional morphologic features of the fovea and optic disc, the layered structure of the retina, and normal anatomic variations in retinal and retinal nerve fiber layer thicknesses with 10-microns depth resolution.

CONCLUSION:

Optical coherence tomography is a potentially useful technique for high depth resolution, cross-sectional examination of the fundus.

PMID:
7887846
[Indexed for MEDLINE]

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