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Acta Neurol Scand. 1994 Nov;90(5):312-7.

Intracranial gliomas in Ferrara, Italy, 1976 to 1991.

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1
Institute of Neurology Clinic, University of Ferrara, Italy.

Abstract

INTRODUCTION:

We planned a descriptive study on the incidence of intracranial gliomas spanning a 16-year period (1976-1991) in the Local Health Service 31 of Ferrara, Northern Italy.

MATERIAL AND METHODS:

We used a complete enumeration approach by reviewing all the possible sources of case collection available in the study area.

RESULTS:

The mean annual incidence rate was 5.8 new cases per 100,000 population (6.96 for men and 4.78 for women; p < 0.05), resulting in 4.7 per 100,000 when directly adjusted to the Italian population. The age-specific incidences showed a small peak in childhood, an increase with age, reaching a maximum in the age group 60 to 64 and then a decline in the elderly. This pattern is similar for both sexes. The adjusted rates increased from 3.94 per 100,000 population in the first five-year period to 5.6 per 100,000 in the third (a nonsignificant difference). The distribution of cases within the study area was substantially uniform.

CONCLUSION:

The incidence rates of Ferrara fell into the middle-high values so far reported and confirmed the male preponderance found in previous studies. The age-related pattern is similar to that observed, with few exceptions, in other surveys. Like other authors we did not find a significant temporal trend, although the incidence rates tended to increase with time. The data encourage further, wider epidemiological studies of a prospective nature.

[Indexed for MEDLINE]

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